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KMID : 1037420070020010052
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Journal of Korean Skull Base Society
2007 Volume.2 No. 1 p.52 ~ p.56
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Radiation Induced Osteogenic Sarcoma Presenting as a Melanoma in Orbital Area
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Shin Il-Young
Park Dong-Hyuk
Chung Yong-Gu
Jung Kwang-Yoon
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Abstract
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Introduction: Postirradiation osteosarcoma arising after nasopharyngeal cancer is rare and seldom reported.
Case presentation: We report irradiation induced osteosarcoma involving the orbit, ethmoid, maxilla and mandible following treatment of melanoma in 45-years-old woman who presented with foul discharge in previous operation site. We present the clinical history, physical findings, imaging studies, and pathologic findings in a patient found to have osteogenic sarcoma of the maxillary sinus and peri-orbit after radiation therapy for a maxillary melanoma.
Conclusion: Osteogenic sarcoma is a rare and late complication of radiation treatment. Although radiotherapy remains an effective adjuvent treatment in patients with tumor, particularly those with residual or recurrent tumor, potential complications must be acknowledged.
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KEYWORD
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Osteosarcoma, maxillary cancer, radiotherapy, surgical excision
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